Oklahoma Louis Stokes Alliance for Minority Participation (OK-LSAMP) Program
Recent Submissions
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Synthesizing Tetraphenylporphyrins and Metalloporphyrins using microwave and ultrasonic reactors
(Oklahoma State University, 2022-10-01)Tetraphenylporphyrin (TPP) is a macrocyclic molecule found in biological compounds. TPP's UV-Vis spectrum ranges from 380-500 nanometers. Metalloporphyrins (MeP) are considered “bioinspired oxidation catalysts” and are ... -
Understanding awareness of food security resources available to university students
(Oklahoma State University, 2022-04-19)Food insecurity is a prevalent issue in college campuses across the country. The Hunger on Campus study found that 48% of college students face food insecurity. Oklahoma State University (OSU) also experiences high rates ... -
Microplastic extraction from sediments with a continuous flow elutriation process
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Analysis of heme-binding proteins from Listeria monocytogenes using differential scanning calorimetry
(Oklahoma State University, 2021-10-09)Listeria monocytogenes is a gram-positive bacterium that can cause severe infection in immunocompromised individuals. It is reliant on the acquisition of iron from its host to continuously spread throughout the body. Here ... -
Tagging endogenous mitochondrial proteins using CRISPR/Cas9 technology
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Synthesis, purification, and characterization of guest molecules for inclusion in cucurbit[n]urils
(Oklahoma State University, 2021-10-09)Cucurbit[n]uril (CB[n]) is a unique macrocycle that can bind small molecules with promising potential applications in drug delivery, molecular machines, and smart materials. This work focuses on the supramolecular equilibrium ... -
Antifungal activity of novel compound EIPE-1 against Cryptococcus neoformans
(Oklahoma State University, 2021-10-09)Cryptococcus neoformans is an opportunistic fungal pathogen of the respiratory tract, which is responsible for over 200,000 deaths annually. Antifungal drugs have been used to treat fungal infections for many decades; ... -
Preliminary exploration of molecular mechanism of the anticancer activity of a novel lead lactate dehydrogenase inhibitor against pancreatic cancer
(Oklahoma State University, 2021-10-09)Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death in the United States, with a long-term survival rate of just under 10%. Chemotherapy is one of the standard treatment options for pancreatic ... -
Discovery and characterization of novel fungal diversity in the equine alimentary tract
(Oklahoma State University, 2021-10-09)Fungi provide crucial ecosystem services in multiple ecosystems. Most fungi thrive as free-living organisms, but many forge symbiotic, predatory, pathogenic, and commensal relationships with algae, plants, and animals. One ... -
Bacterial two hybrid analysis of Chlamydia trachomatis proteins
(Oklahoma State University, 2021-10-09)Chlamydia trachomatis is an obligate intracellular bacterial pathogen which poses severe health problems throughout the world. There are over 90 million new cases annually, making it the most common sexually transmitted ... -
Using fluorescent UPEC as a model to study interactions with human bladder cells
(Oklahoma State University, 2021-10-09)Escherichia coli (E. coli) are opportunistic bacteria that reside in the intestines of humans and contribute to gastrointestinal health. However, there are some strains that can cause a variety of diseases including urinary ... -
Studying the effects of antibiotics on mitochondrial inhibitors
(Oklahoma State University, 2021-10-09)The usage of ivermectin (ivm) to treat COVID-19 is controversial. According to a study, ivermectin helped treat COVID-19, but clinical trials showed that ivermectin with the tetracycline-class antibiotic doxycycline overcame ... -
Enzymatic assessment of cells with distinct TP53 mutations
(Oklahoma State University, 2021-10-09)The p53 transcription factor, encoded by the human gene TP53, is the most commonly mutated gene in human cancers. Once the TP53 gene is mutated, p53 proteins not only lose their tumor suppression abilities but can also ... -
Screening Warrior Hops for inhibitors of cancer cell metabolism
(Oklahoma State University, 2021-10-09)The purpose of this project is to examine the effects of components of Warrior Hops on cancer cell metabolism to better understand the mechanism of infection for SARSCoV-2. In h293 cells (human embryonic kidney cells that ... -
Effects of light intensity on the morphology, growth rate and phenolic content of Zygnema
(Oklahoma State University, 2021-10-09)Zygnema is a freshwater alga that forms thick mats that float at the water surface. Cells located at the surface of mats are exposed to very high visible light and UVB compared to cells deep within the mats. Previous studies ... -
Construction of a reusable Gel-Eluted Liquid Fraction Entrapment Electrophoresis (GELFrEE) using 3D printing
(Oklahoma State University, 2021-10-09)Gel-Eluted Liquid Fraction Entrapment (GELFrEE) is commonly utilized in proteomics research for size-based separation and fractionation of proteins. Commercial GELFrEE cartridges are wasteful due to their single-use ... -
Investigation of the mechanical, collagen microstructural, and morphological properties of human intracranial aneurysms
(Oklahoma State University, 2021-10-09)Intracranial aneurysms (ICAs) are focal dilations of cerebral arteries caused by the weakening of the arterial wall. The resulting changed hemodynamics can further lead to stress and growth of the site until it eventually ... -
Comparison study of 1999-2019 suicide rate per 100,000 population between Native American and other races in the United States of America
(Oklahoma State University, 2021-10-09)The suicide rate in the USA has been on the rise, which affects specific age groups, genders, and race/ethnicity. Native American (NA) has been known to be on a higher level than the other races. This study focuses on ... -
Quantitative assessment of otitis media with effusion with scanning laser Doppler vibrometer - A preliminary study
(Oklahoma State University, 2021-10-09)Otitis media with effusion (OME) is a common middle ear inflammation for preschool-age children, with the presence of fluid in the middle ear cavity (MEC). Although the biomechanical abnormalities induced by OME has been ... -
Viral oncoprotein Tax and regulation of the HTLV promoter
(Oklahoma State University, 2021-10-09)Tax, an oncoprotein virally expressed from Human T-cell Leukemia Virus (HTLV), is a transcriptional regulator with incompletely understood functions in host cells. HTLV is a retrovirus of clade deltraretroviradae with two ...